منابع مشابه
Metabolic gene profile in early human fetal heart development.
The primitive cardiac tube starts beating 6-8 weeks post fertilization in the developing embryo. In order to describe normal cardiac development during late first and early second trimester in human fetuses this study used microarray and pathways analysis and created a corresponding 'normal' database. Fourteen fetal hearts from human fetuses between 10 and 18 weeks of gestational age (GA) were ...
متن کاملMetabolic gene expression in fetal and failing human heart.
BACKGROUND Previous studies suggest that the failing heart reactivates fetal genes and reverts to a fetal pattern of energy substrate metabolism. We tested this hypothesis by examining metabolic gene expression profiles in the fetal, nonfailing, and failing human heart. METHODS AND RESULTS Human left ventricular tissue (apex) was obtained from 9 fetal, 10 nonfailing, and 10 failing adult hear...
متن کاملEarly oleate deficiency leads to severe defects in fetal rat liver development
Objective(s): Oleate can be produced through de novo synthesis, which contributes to biological processes and signaling pathways. However, the role of this non-essential fatty acid in hepatic development remains unclear. The current study aimed to evaluate the influence of early oleate deficiency induced by the inhibitor of de novo oleate synthesis MF-438 on fetal rat ...
متن کاملThe Early Fetal Development of Human Neocortical GABAergic Interneurons
GABAergic interneurons are crucial to controlling the excitability and responsiveness of cortical circuitry. Their developmental origin may differ between rodents and human. We have demonstrated the expression of 12 GABAergic interneuron-associated genes in samples from human neocortex by quantitative rtPCR from 8 to 12 postconceptional weeks (PCW) and shown a significant anterior to posterior ...
متن کاملEmbryonic and early fetal development of the human neocortex.
Early corticogenesis was studied in human embryos and early fetuses from Carnegie stages 16 to 22 (5-8 gestational weeks) by using immunohistochemistry for Reelin (Reln), calretinin (CR), and glutamic acid decarboxylase (GAD). A first population of Reln-positive cells appears in the neocortical anlage at stage 16 and increases in number at stages 17-18. At stages 19-20, a monolayer of horizonta...
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ژورنال
عنوان ژورنال: MHR: Basic science of reproductive medicine
سال: 2014
ISSN: 1460-2407,1360-9947
DOI: 10.1093/molehr/gau026